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Search Results for " tumor growth "

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VEGFR FGFR

543

阻害剤

天然化合物

573

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T7611	ODM-203		VEGFR , FGFR
	ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity		VEGFR , FGFR
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T4288	HVEGF-IN-1		VEGFR
	hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.		VEGFR
T1792L	Regorafenib monohydrate		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T6932	PD168393		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
TQ0059	Ilorasertib	ABT-348	VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
	Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...		VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
T9927	Panitumumab		EGFR
	Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).		EGFR
T9473	4SC-203		FLT
	4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...		FLT
T11279	FGFR1/DDR2 inhibitor 1		Discoidin Domain Receptor (DDR) , FGFR , Others
	FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.		Discoidin Domain Receptor (DDR) , FGFR , Others
T1792	Regorafenib	BAY 73-4506,Fluoro-Sorafenib	Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T7322	Theliatinib		EGFR
	Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.		EGFR
T8872	(Rac)-JBJ-04-125-02	JBJ-04-125-02	EGFR
	(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.		EGFR
T2490	Osimertinib	AZD-9291,Mereletinib	EGFR
	Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi...		EGFR
T26296	Triparanol	MER-29,NSC 65345,NSC-65345,NSC65345	Apoptosis , Hedgehog/Smoothened
	Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparan...		Apoptosis , Hedgehog/Smoothened
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T6626	PF-3758309	PF-309,PF-03758309,PF 3758309	Apoptosis , PAK
	PF-3758309 (PF-03758309) (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.		Apoptosis , PAK
T4230	PF-3758309 hydrochloride	PF-03758309 hydrochloride	Apoptosis , PAK
	PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hyd...		Apoptosis , PAK
T1950	PND-1186	PND1186,PND 1186,VS-4718,SR-2516	Apoptosis , FAK
	PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).		Apoptosis , FAK
T0446	Naphazoline hydrochloride	Albalon,Rhinantin,Naphazoline HCl	Adrenergic Receptor
	Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.		Adrenergic Receptor
T21445	Naphazoline	AK-Con,Naphcon-a,Clear Eyes,All Clear	Adrenergic Receptor
	Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.		Adrenergic Receptor
T3634	Osimertinib mesylate	Mereletinib mesylate,AZD-9291 mesylate	EGFR
	Osimertinib mesylate (Mereletinib mesylate) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).		EGFR
T0373	Erlotinib	OSI-744,NSC 718781,CP358774,R1415	EGFR , Autophagy
	Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T9922	Matuzumab		EGFR
	Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR frequently associated with the growth of blood vessels in malignancy facilitating tumor growth and survival.		EGFR
T6517	Golvatinib	E-7050	VEGFR , c-Met/HGFR
	Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ...		VEGFR , c-Met/HGFR
T2576	Brivanib (alaninate)	BMS-582664,Brivanib Alaninate	VEGFR , FGFR , Autophagy
	Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...		VEGFR , FGFR , Autophagy
T64295	Talotrexin ammonium		DHFR
	Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, he...		DHFR
T64357	FA16	FA 16,FA-16	Ferroptosis
	FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system...		Ferroptosis
T9463	6-HYDROXYLAMINOURACIL		Others
	6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.		Others
T9963	MPT0B390		HDAC
	MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.		HDAC
T41277	PACMA 31		Others
	PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.		Others
T15030	CycLuc1		Others
	CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts.		Others
T24642	YH-306	YH306,TRV055 acetate (25849-90-5 Free base)	MMP , MMP , FAK , Rho , PI3K , Src
	YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.		MMP , MMP , FAK , Rho , PI3K , Src
T12205	Ned 19		Calcium Channel
	Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice.		Calcium Channel
T28396	PGP-4008	PGP 4008,PGP4008	P-gp
	PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.		P-gp
T10638	BY27		Epigenetic Reader Domain
	BY27 is a potent and selective BET BD2 inhibitor (Ki: 3.1 nM) with anticancer activity, inhibits BD1/BD2 of BRD2, BRD3, BRD4 and BRDT, and suppresses tumor growth.		Epigenetic Reader Domain
T13393	ZEN-3411		Epigenetic Reader Domain
	ZEN-3411 is an orally available and potent BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.		Epigenetic Reader Domain
T11209	EOAI3402143		DUB
	EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth.		DUB
T8340	Quinocetone		Others , Antibacterial , Antibiotic
	Quinocetone is an animal growth promoter and potential anti-tumor activity.		Others , Antibacterial , Antibiotic
T12430	PF-06821497		Histone Methyltransferase
			Histone Methyltransferase
T40286	KRAS G12C inhibitor 19		Ras
	KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in cellular assays, and the family inhibits tumor growth.		Ras
TP1472	Tyroserleutide		Others
	Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of h...		Others
T34602	Selatinib		EGFR
	Selatinib is an orally active and potent dual inhibitor of EGFR and ErbB2 with anticancer activity that inhibits the growth of NCI-N87 tumor cells.		EGFR
T20158	Phenformin	Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps	Apoptosis
	Phenformin (BRN 1977317) is a biguanide compound with anticancer and anti-glycemic activity, inhibits skin tumor growth and promotes keratinocyte differentiation and apoptosis.		Apoptosis
T4235	Roblitinib	FGF-401	FGFR
	Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...		FGFR
T10313	AMXT-1501 tetrahydrochloride		Others
	AMXT-1501 tetrahydrochloride is an inhibitor of polyamine transport. It blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells.		Others
T29797	AKB-6899	AKB6899	VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF
	AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which in...		VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF
T14885	CBS9106	Felezonexor,SL-801	CRM1
	CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs th...		CRM1
T82008	JG-2016		Histone Acetyltransferase
	JG-2016, as a small molecule histone acetyltransferase 1 (HAT1) inhibitor, inhibits the growth of human cancer cell lines, inhibits enzyme activity in cellulose, and interferes with tumor growth.		Histone Acetyltransferase
T2267	BQU57		GTPase , Ras
	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.		GTPase , Ras

Compounds

Target: Apoptosis, VEGFR

Regorafenib monohydrate

T1792L

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

PD168393

T6932

Synonym:

Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy

Ilorasertib

TQ0059

Synonym: ABT-348

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

FGFR1/DDR2 inhibitor 1

T11279

Synonym:

Target: Discoidin Domain Receptor (DDR), FGFR, Others

Regorafenib

T1792

Synonym: BAY 73-4506,Fluoro-Sorafenib

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Synonym: JBJ-04-125-02

Target: EGFR

Osimertinib

T2490

Synonym: AZD-9291,Mereletinib

Target: EGFR

Triparanol

T26296

Synonym: MER-29,NSC 65345,NSC-65345,NSC65345

Target: Apoptosis, Hedgehog/Smoothened

ON123300

T6920

Synonym:

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

PF-3758309

T6626

Synonym: PF-309,PF-03758309,PF 3758309

Target: Apoptosis, PAK

PF-3758309 hydrochloride

T4230

Synonym: PF-03758309 hydrochloride

Target: Apoptosis, PAK

PND-1186

T1950

Synonym: PND1186,PND 1186,VS-4718,SR-2516

Target: Apoptosis, FAK

Naphazoline hydrochloride

T0446

Synonym: Albalon,Rhinantin,Naphazoline HCl

Target: Adrenergic Receptor

Naphazoline

T21445

Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear

Target: Adrenergic Receptor

Osimertinib mesylate

T3634

Synonym: Mereletinib mesylate,AZD-9291 mesylate

Target: EGFR

Erlotinib

T0373

Synonym: OSI-744,NSC 718781,CP358774,R1415

Target: EGFR, Autophagy

Target: VEGFR, c-Met/HGFR

Brivanib (alaninate)

T2576

Synonym: BMS-582664,Brivanib Alaninate

Target: VEGFR, FGFR, Autophagy

6-HYDROXYLAMINOURACIL

Synonym: YH306,TRV055 acetate (25849-90-5 Free base)

Target: MMP, MMP, FAK, Rho, PI3K, Src

Ned 19

T12205

Synonym:

Target: Calcium Channel

PGP-4008

T28396

Synonym: PGP 4008,PGP4008

Target: Epigenetic Reader Domain

ZEN-3411

T13393

Synonym:

Target: Epigenetic Reader Domain

Target: Others, Antibacterial, Antibiotic

PF-06821497

T12430

Synonym:

Target: Histone Methyltransferase

KRAS G12C inhibitor 19

Synonym: Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps

AMXT-1501 tetrahydrochloride

Target: VEGFR, HIF/HIF Prolyl-Hydroxylase, HIF

CBS9106

T14885

Synonym: Felezonexor,SL-801

Target: Histone Acetyltransferase

カタログ番号	製品名	別名	ターゲット
T19470	Nandrolone propionate		Others , Androgen Receptor
	Nandrolone propionate is an anabolic steroid action primarily consisting of androgenic and nitrogen-retentive properties.		Others , Androgen Receptor
TN2132	Quinizarin	1,4-Dihydroxyanthraquinone	Others , DNA/RNA Synthesis , Antifungal
	Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product		Others , DNA/RNA Synthesis , Antifungal
T3912	Saikosaponin B1		Others
	Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.		Others
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
TWA2417	Sodium taurocholate	Taurocholate Sodium	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...		Others
T32291	Jineol	NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081	Others
	Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.		Others
TN1017	Physion 8-O-β-D-glucoside	Physcion 1-O-beta-D-glucoside	Others
	Physion 8-O-β-D-glucoside is a tumor cell growth inhibitor.		Others
TQ0065	Pseudobufarenogin	ψ-Bufarenogin	Others
	Pseudobufarenogin (ψ-Bufarenogin), a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.		Others
T4863	DL-Homocysteine	2-Amino-4-mercaptobutyric acid	Endogenous Metabolite
	DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.		Endogenous Metabolite
TN2326	(Z)-Butylidenephthalide	(Z)-3-Butylidenephthalide	Glucosidase
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.		Glucosidase
TN6714	Geranylgeraniol	FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095	Apoptosis
	Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...		Apoptosis
T4S1519	Pseudoginsenoside RT5		Others
	1. Pseudoginsenoside RT5 has anti-epilepsy, anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor and anti-malaria activities.		Others
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	Apoptosis , P450
	(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.		Apoptosis , P450
TN7052	Crocin III	Crocetin-mono-(β-D-gentiobiosyl)-ester	Others
	Crocin III (Crocetin-mono-(β-D-gentiobiosyl)-ester) is a crocin derived from saffron (Crocus sutivus L.). Crocins inhibit the cell growth of tumor cells and have anti-inflammatory activity.		Others
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
T0190	Vinorelbine	KW-2307 base	Microtubule Associated
	Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase.		Microtubule Associated
TN1560	Dehydroeffusol	5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol	MMP , ERK , GPR , Others
	Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reti...		MMP , ERK , GPR , Others
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
T2336	Vitamin K2	Menatetrenone	Endogenous Metabolite
	Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several...		Endogenous Metabolite
T0650	Phenyl acetate	Acetylphenol,Phenol acetate,Acetic acid phenyl ester	Others , Endogenous Metabolite
	Phenyl acetate (Acetic acid phenyl ester) is an aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibi...		Others , Endogenous Metabolite
T7984	2-Hydroxyflavanone		Others
	2-Hydroxyflavanone is a naturally occurring flavonoid found in many plants and fruits. It has antioxidant, anti-inflammatory and anti-tumor activity, scavenging free radicals, reducing inflammation and inhibiting the gro...		Others
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase
TQ0099	20-O-Acetylingenol-3-angelate	Euphorbia factor Pe1	Others
	20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, ...		Others
T3S1955	7-Ethylcamptothecin		Others
	1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothecin remains in the intestinal tract for a ...		Others
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
T7961	N4-Benzoyl-2′-deoxycytidine		Others
	N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b...		Others
T5530	Mithramycin A	Plicamycin	DNA/RNA Synthesis
	Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is...		DNA/RNA Synthesis
T3604	Sodium dichloroacetate	Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)	Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
	Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...		Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
T2978	Mogroside V		AMPK
	Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the potential to protect against LPS-induce...		AMPK
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T2220	2-Methoxyestradiol	NSC-659853,2-MeOE2,2-ME2	Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
	2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T6S0033	Crotonoside	Isoguanosine,2-HYDROXYADENOSINE	Others , FLT , HDAC
	1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stim...		Others , FLT , HDAC
T6718	Zingerone	Gingerone,Vanillylacetone,NSC 15335	NF-κB
	Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gi...		NF-κB
T6S1784	Brazilin	Natural Red 24,Braziletto,Brasilin,Superbresiline	Apoptosis , Others , AMPK , Autophagy
	1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific sign...		Apoptosis , Others , AMPK , Autophagy
T3976	Cytosporone B	Csn-B,Dothiorelone G	Others
	Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene...		Others
TN1853	Lariciresinol		VEGFR , Antifection
	Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious disease...		VEGFR , Antifection
T23773	Barbigerone	Barubigeron
	Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
T24744	Rubone
	Rubone is the tumor suppressor miRNA-34a modulator that acts by inhibiting the growth of hepatocellular carcinoma.
TN4603	Myricanol		BCL , VEGFR , Caspase , HIF
	Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.		BCL , VEGFR , Caspase , HIF
T24002	Disermolide	XAA 296,XAA296,XAA-296
	Disermolide is a polyketide natural product found to stabilize microtubules. Disermolide was found to be a potent inhibitor of tumor cell growth in several MDR cancer cell lines.
T27977	Manzamine A	Keramamine A
	Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram nega...
TN4839	Psidial A		Others
	Psidial A shows activity to enzyme PTP1B; it also reduces tumor growth and stimulate uterus proliferation.		Others
TN3834	Derrone		Antifection
	Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 t...		Antifection
TN1615	Epitheaflagallin 3-O-gallate		MMP
	Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis.		MMP
T7935	2-Aminothiazol-4-acetic acid		Others
	2-Aminothiazol-4-acetic acid acts by inhibiting the activity of certain enzymes and proteins related to inflammation, tumor growth and oxidative stress, and has anti-inflammatory, anti-tumor and anti-fungal activities.		Others
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天然物製品

Nandrolone propionate

T19470

Synonym:

Target: Others, Androgen Receptor

Quinizarin

TN2132

Synonym: 1,4-Dihydroxyanthraquinone

Target: Others, DNA/RNA Synthesis, Antifungal

Target: EGFR, Tyrosine Kinases, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Synonym: Taurocholate Sodium

Target: Others

Jineol

T32291

Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081

Target: Others

Physion 8-O-β-D-glucoside

TN1017

Synonym: Physcion 1-O-beta-D-glucoside

Target: Others

Pseudobufarenogin

TQ0065

Synonym: ψ-Bufarenogin

Target: Others

DL-Homocysteine

T4863

Synonym: 2-Amino-4-mercaptobutyric acid

Target: Endogenous Metabolite

(Z)-Butylidenephthalide

TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

Geranylgeraniol

TN6714

Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095

Target: Apoptosis

Pseudoginsenoside RT5

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

(E)-Flavokawain A

T5715

Synonym: FLAVOKAVAIN A(P)

Target: Apoptosis, P450

Crocin III

TN7052

Synonym: Crocetin-mono-(β-D-gentiobiosyl)-ester

Target: Others

9-hydroxy-4-androstene-3,17-dione

Synonym: KW-2307 base

Target: Microtubule Associated

Dehydroeffusol

TN1560

Synonym: 5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol

Target: MMP, ERK, GPR, Others

Halofuginone hydrobromide

T3524

Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Isodeoxyelephantopin

TN1141

Synonym:

Target: NF-κB, Reactive Oxygen Species, Autophagy

Vitamin K2

T2336

Synonym: Menatetrenone

Target: Endogenous Metabolite

Phenyl acetate

T0650

Synonym: Acetylphenol,Phenol acetate,Acetic acid phenyl ester

Target: Others, Endogenous Metabolite

β,β-Dimethylacrylshikonin

T3S2344

Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

20-O-Acetylingenol-3-angelate

TQ0099

Synonym: Euphorbia factor Pe1

Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR

N4-Benzoyl-2′-deoxycytidine

Target: DNA/RNA Synthesis

Sodium dichloroacetate

T3604

Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

2-Methoxyestradiol

T2220

Synonym: NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

Crotonoside

T6S0033

Synonym: Isoguanosine,2-HYDROXYADENOSINE

Target: Others, FLT, HDAC

Zingerone

T6718

Synonym: Gingerone,Vanillylacetone,NSC 15335

Target: NF-κB

Brazilin

T6S1784

Synonym: Natural Red 24,Braziletto,Brasilin,Superbresiline

Target: Apoptosis, Others, AMPK, Autophagy

Cytosporone B

T3976

Synonym: Csn-B,Dothiorelone G

Target: VEGFR, Antifection

Target: BCL, VEGFR, Caspase, HIF

Disermolide

T24002

Synonym: XAA 296,XAA296,XAA-296

Target:

Manzamine A

T27977

Synonym: Keramamine A

Epitheaflagallin 3-O-gallate

TN1615

Synonym:

Target: MMP

2-Aminothiazol-4-acetic acid

T7935

Synonym:

Target: Others

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPJ-01166	IGFBP-7 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ...
TMPK-00782	PLAU/uPA Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-04644	PDGFB Protein, Human, Recombinant (His)	Human	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPY-02474	ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-04168	ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-03382	FGF-6 Protein, Human, Recombinant	Human	E. coli
	FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPY-02432	VEGF164 Protein, Rat, Recombinant	Rat	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01717	VEGF164 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-05588	EphA2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Eph receptor A2 (Ephrin type-A receptor 2 or EphA2) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptors' corresponding family of ligands are the ephrins anchored to cell ...
TMPY-01321	DLL4 Protein, Human, Recombinant (His)	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-03104	FGF-17 Protein, Human, Recombinant	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated	Human,Cynomolgus	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-03698	VEGF121b Protein, Human, Recombinant	Human	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-02626	FGF-18 Protein, Human, Recombinant (His)	Human	HEK293
	Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-06935	FGF-21 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-01786	EphB4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephr...
TMPY-04803	DLL4 Protein, Human, Recombinant	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00804	FGF-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell sur...
TMPY-01337	DLL4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00776	DLL4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-02907	FGF-19 Protein, Human, Recombinant	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-04722	DcR1/TRAILR3 Protein, Human, Recombinant (His)	Human	HEK293
	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ...
TMPY-02112	FGFR4 Protein, Human, Recombinant (His)	Human	HEK293
	Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP...
TMPY-06842	BMP-4 Protein, Human, Recombinant (E399D)	Human	E. coli
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His)	Human	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant	Human,Rhesus,Cynomolgus,Canine	CHO
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04413	IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)	Human	Baculovirus-Insect Cells
	Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-04753	IRE1 Protein, Human, Recombinant (aa 465-977)	Human	Baculovirus-Insect Cells
	Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E.coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His)	Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant	Mouse,Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-04645	TL1A/TNFSF15 Protein, Human, Recombinant (hFc)	Human	HEK293
	TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
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TL1A/TNFSF15 Protein, Mouse, Recombinant

TMPJ-00603

Species: Mouse

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)

TMPJ-01312

Species: Mouse

Expression System: Human Cells

IGFBP-7 Protein, Mouse, Recombinant (His)

TMPJ-01166

Species: Mouse

Expression System: Human Cells

PLAU/uPA Protein, Mouse, Recombinant (His & Avi)

TMPK-00782

Species: Mouse

Expression System: HEK293

PDGFB Protein, Human, Recombinant (His)

TMPY-04644

Species: Human

Expression System: Yeast

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus-Insect Cells

TGF alpha Protein, Human, Recombinant

TMPY-03958

Species: Human

Expression System: E. coli

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)

TMPY-02474

Species: Mouse

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-04168

Species: Cynomolgus,Rhesus

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

TMPY-00664

Species: Human

Expression System: HEK293

FGF-6 Protein, Human, Recombinant

TMPY-03382

Species: Human

Expression System: E. coli

VEGF164 Protein, Rat, Recombinant

TMPY-02432

Species: Rat

Expression System: Baculovirus-Insect Cells

VEGF164 Protein, Mouse, Recombinant

TMPY-01717

Species: Mouse

Expression System: Baculovirus-Insect Cells

EphA2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05588

Species: Human

Expression System: HEK293

DLL4 Protein, Human, Recombinant (His)

TMPY-01321

Species: Human

Expression System: HEK293

TGFBR1 Protein, Human, Recombinant (mFc & Avi)

TMPK-00305

Species: Human

Expression System: HEK293

FGF-17 Protein, Human, Recombinant

TMPY-03104

Species: Human

Expression System: E. coli

VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-04911

Species: Human,Cynomolgus

Expression System: HEK293

VEGF121b Protein, Human, Recombinant

TMPY-03698

Species: Human

Expression System: HEK293

FGF-18 Protein, Human, Recombinant (His)

TMPY-02626

Species: Human

Expression System: HEK293

FGF-21 Protein, Human, Recombinant

TMPY-06935

Species: Human

Expression System: E. coli

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293

EphB4 Protein, Mouse, Recombinant (hFc)

TMPY-01786

Species: Mouse

Expression System: HEK293

DLL4 Protein, Human, Recombinant

TMPY-04803

Species: Human

Expression System: HEK293

FGF-9 Protein, Human, Recombinant (hFc)

TMPY-00804

Species: Human

Expression System: HEK293

DLL4 Protein, Mouse, Recombinant (His)

TMPY-01337

Species: Mouse

Expression System: HEK293

DLL4 Protein, Human, Recombinant (hFc)

TMPY-00776

Species: Human

Expression System: HEK293

VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: Human Cells

FGF-19 Protein, Human, Recombinant

TMPY-02907

Species: Human

Expression System: E. coli

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: Human Cells

DcR1/TRAILR3 Protein, Human, Recombinant (His)

TMPY-04722

Species: Human

Expression System: HEK293

FGFR4 Protein, Human, Recombinant (His)

TMPY-02112

Species: Human

Expression System: HEK293

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

TMPY-02483

Species: Human

Expression System: Baculovirus-Insect Cells

BMP-4 Protein, Human, Recombinant (E399D)

TMPY-06842

Species: Human

Expression System: E. coli

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

TMPY-01936

Species: Mouse

Expression System: HEK293

Latent TGF beta 1 Protein, Mouse, Recombinant (His)

TMPY-00500

Species: Mouse

Expression System: HEK293

Latent TGF beta 1 Protein, Human, Recombinant (His)

TMPY-01133

Species: Human

Expression System: HEK293

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

TMPY-02638

Species: Human,Rhesus,Cynomolgus,Canine

Expression System: CHO

IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)

TMPY-04413

Species: Human

Expression System: Baculovirus-Insect Cells

IRE1 Protein, Human, Recombinant (aa 465-977)

TMPY-04753

Species: Human

Expression System: Baculovirus-Insect Cells

ITGB1 Protein, Human, Recombinant (His)

TMPY-00476

Species: Human

Expression System: HEK293

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E.coli

IGFBP-3 Protein, Human, Recombinant (His)

TMPY-00835

Species: Human

Expression System: HEK293

Latent TGF beta 1 Protein, Rat, Recombinant (His)

TMPY-03945

Species: Rat

Expression System: HEK293

Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

TMPY-04211

Species: Cynomolgus

Expression System: HEK293

TGF beta 1 Protein, Rat/Mouse, Recombinant

TMPY-00608

Species: Mouse,Rat

Expression System: HEK293

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

TL1A/TNFSF15 Protein, Human, Recombinant (hFc)

TMPY-04645

Species: Human

Expression System: HEK293

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

TMPY-01613

Species: Mouse

Expression System: HEK293

--------- More ---------

カタログ番号	製品名
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L2100	Anti-Cancer Compound Library	7234 compounds
	A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L6120	Flavonoid Natural Product Library	477 compounds
	A unique collection of 477 flavonoids can be used for high throughput and high content screening；
L6750	PBCRBS Traditional Chinese Medicine Compound Library	580 compounds
	A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.

ライブラリー

Angiogenesis related Compound Library

L4800

Compounds: 1353

Anti-Cancer Compound Library

L2100

Compounds: 7234

Flavonoid Natural Product Library

L6120

Compounds: 477

PBCRBS Traditional Chinese Medicine Compound Library

L6750

Compounds: 580